US Pharm. 2013;38(8):6.
Jupiter, FL—Researchers at the Scripps Research
Institute in Jupiter, Florida, are developing a drug that mimics the
benefits of exercise with no actual workout required. According to a
study published in Nature Medicine, obese mice were injected with
a compound that increased production of the muscle protein REV-ERB,
which is known to partially control circadian rhythms and internal
biological clocks. These animals lost weight, improved their cholesterol
levels, and expended 5% more energy compared to mice in the control
group, even though they were not exercising more. While it is still
unclear whether or not the drug can be safely used in humans, the
fundamental goal is to help disabled people experience some of the
health benefits of exercise, not aid those who want to avoid physical
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