U.S. Pharmacist

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Agency Approves Drug for Adult ADHD

Staff

8/19/2008

US Pharm. 2008;33(8):23. 

The FDA has broadened the indications for methylphenidate (Concerta) extended-release tablets in doses of 18 mg to 72 mg/day to include adults with attention-deficit hyperactivity disorder (ADHD). Methylphenidate was already approved for treatment of ADHD in children ages 6 to 18. Clinical trial data showed that the drug significantly improved ADHD symptoms such as inattention, impulsivity, and hyperactivity compared with placebo in patients aged 18 to 65.

The most common adverse reactions in adults were dry mouth, nausea, decreased appetite, headache, and insomnia.

Methylphenidate is contraindicated in patients with significant anxiety, tension, or agitation; glaucoma; tics; Tourette's syndrome (TS) or a family history of TS; current or past use of monoamine oxidase inhibitors; or narrowing of the esophagus, stomach, or intestine.

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U.S. Pharmacist is a monthly journal dedicated to providing the nation's pharmacists with up-to-date, authoritative, peer-reviewed clinical articles relevant to contemporary pharmacy practice in a variety of settings, including community pharmacy, hospitals, managed care systems, ambulatory care clinics, home care organizations, long-term care facilities, industry and academia. The publication is also useful to pharmacy technicians, students, other health professionals and individuals interested in health management. Pharmacists licensed in the U.S. can earn Continuing Education credits through Postgraduate Healthcare Education, LLC, accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education.

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