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Issue:  October 2010 •  Archive  •  Subscribe •  Unsubscribe
In This Edition Featured Article Featured CE
•  Editor's Notebook
•  Counseling Pearls
•  It's the Law
•  Clinical Corner
•  Consult Your Pharmacist
•  Educational Spotlight
•  Quick Poll
     - Medical Marijuana
  Photo New Drug Review 2010
This article reviews new drugs approved by the FDA in the past year.
  Photo Medical Marijuana: Therapeutic Uses and Legal Status
State laws permitting personal medical use are at variance with existing federal laws.


Editor's Notebook
It Really Is a Small World

Pharmacists worldwide are active participants in their countries' health care systems.
Counseling Pearls
Photo Aspirin for Primary Prevention in Diabetes

Diabetes affects nearly 24 million people in the United States. Low-dose aspirin is recommended for patients at increased cardiovascular risk.
Photo Vitamin D Supplementation: An Update

This hormone is important for overall health and prevention of a number of chronic diseases. Many health care providers have increased their intake recommendations.
It's the Law
Rogue Pharmacists

We must not allow a few bad apples to spoil the integrity of the pharmacy profession.
Clinical Corner
Photo IVIG Use in Renal Insufficiency or Transplantation

Intravenous immunoglobulin has been in short supply for years, which poses treatment dilemmas. Pharmacists must advise providers regarding the use of alternative products, when necessary.
Photo Review of Selected NMEs 2010

The basic clinical and pharmacologic profiles, pharmacokinetics, adverse reactions, and dosing of five new molecular entities recently approved by the FDA are discussed.
Consult Your Pharmacist
Recent Rx-to-OTC Product Switches

When a product's status changes, pharmacists should instruct patients about safe use.
Educational Spotlight
Understanding Female Infertility: Causes and Treatments

Reproductive difficulties and related treatments place psychological, physical, and financial challenges on the couple trying to conceive.
HIV/AIDS: A Primer for Pharmacists

An overview of this complex disease's clinical features, diagnosis, and treatment strategies is presented.

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Vitamin B12 May Protect Against Alzheimer's Disease
Stockholm, Sweden — New research published in Neurology indicates that vitamin B12 may reduce the risk of Alzheimer's disease (AD). In a 7-year study led by Babak Hooshmand, MD, of the Karolinska Institute, periodic blood samples were taken from 271 elderly subjects without AD at baseline and tested for homocysteine and holotranscobalamin, the active portion of the vitamin. Vitamin B12 can lower homocysteine, which has been linked to a risk of AD. Subjects with the highest B12 levels were least likely to develop AD. Each micromolar increase in homocysteine concentration increased risk of AD by 16%, whereas each picomolar increase in holotranscobalamin reduced risk by 2%. "More research is needed...before vitamin B12 should be used solely as a supplement to help protect memory," said Hooshmand.
Egg Allergy Does Not Rule Out Flu Vaccine
Milwaukee, WI — The American Academy of Allergy, Asthma & Immunology has determined that most people with egg allergy can safely receive the flu vaccine under the care of an allergist or immunologist. In the past, individuals allergic to eggs were told to avoid flu vaccination because the egg protein in the vaccine could trigger an allergic reaction. However, flu vaccines contain only a tiny amount of egg protein, and recent clinical studies have found that the vast majority of people with egg allergy did not experience a reaction upon immunization. Either a two-step graded challenge or a single, age-appropriate dose may be used for safe administration in egg-allergic patients.
Osteoporosis Drug Builds Bone in Patients With Gum Disease
Ann Arbor, MI — A drug that grows bone in osteoporosis patients also can heal bone wounds in gum disease patients, according to a University of Michigan study. In the study, patients with severe gum disease received either injections of teriparatide—an anabolic osteoporosis drug—into the abdomen or stomach or placebo for 6 weeks. After 1 year, bone-level measurements in the teriparatide group improved by 29% (a 10-fold increase), versus 3% in the placebo group. Until now, it has been very difficult to reverse bone loss from periodontal disease. The next step is to determine whether the teriparatide treatment could be delivered locally to target site-specific bone healing.
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