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Express Scripts and Medco Announce Merger
New York, NY — Express Scripts has announced its intention to buy pharmacy benefits management (PBM) rival Medco Health Solutions for a reported $29.1 billion. The deal, which is expected to close in the first half of 2012 pending approval from regulators and shareholders, would create the world’s largest PBM, Express Scripts Holding Inc. The new company could use its size to negotiate better discounts on drug prices, although it would also have less competition than before. Last year, the two companies processed over 1.7 billion prescriptions, with combined revenue of approximately $110 billion. Express Scripts' largest competitor after the deal would be CVS Caremark Corp., which handled over 585 million claims in 2010. |
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Vaccines for 2011-2012 Flu Season Approved
Gaithersburg, MD— The FDA has approved the formulation for the 2011-2012 influenza vaccine. This formulation protects against the three virus strains that surveillance indicates will be most common during the upcoming season. Six manufacturers are licensed to produce and distribute the influenza vaccine in the United States. This includes Fluzone Intradermal (Sanofi Pasteur Inc.), which uses a microinjection needle to deliver the vaccine into the skin instead of the muscle. This recently approved vaccine system will be available for those 18 to 64 years old. The CDC’s Advisory Committee on Immunization Practices recommends that all individuals 6 months of age and older receive an annual influenza vaccination. |
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Avastin’s Breast Cancer Indication May Be Pulled
Silver Spring, MD—The Oncologic Drug Advisory Committee (ODAC) unanimously recommended that FDA approval of Avastin (bevacizumab) for metastatic breast cancer be withdrawn due to safety and efficacy concerns. In December 2010, another FDA panel made a similar recommendation. The breast cancer indication was originally provided in February 2008 under the FDA's accelerated approval program. The ODAC's recommendation is not the final decision of the FDA. FDA Commissioner Margaret A. Hamburg, MD, is expected to issue her ruling following the closing of the docket for public comment. Any decision will only affect the use of Avastin in relation to breast cancer; its indications for brain, colon, kidney, and lung cancers are not being challenged. |
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