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Issue:  October 2012 •  Archive  •  Subscribe •  Unsubscribe
In This Edition Featured Article Featured CE
•  Editor's Notebook
•  Counseling Pearls
•  It's the Law
•  Clinical Corner
•  Consult Your Pharmacist
•  Educational Spotlight
•  Quick Poll
  – Compounding Pharmacies
  Photo New Drug Review 2012
This article reviews four new drugs that were approved by the FDA in the past year.
  Photo Drug-Induced Osteoporosis: A Review of Medications That Affect Bone Mineral Density
Since most diseases treated with these agents render the occurrence of low BMD more likely, these drugs can further compromise a patient's bone structure.

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Editor's Notebook
Prescription for Disaster

Doctors should not be permitted to dispense medication with any motive for personal gain.
Counseling Pearls
Photo Treatment of Paget's Disease of Bone

Increased bone turnover characterizes this localized disorder of the skeletal system, also known as osteitis deformans. A single bone or multiple bones may be involved.
Photo Senior Care—Focus on the Foot: Changes With Age and Disease

Age-related changes of the foot and manifestations of systemic disease cause problems including pain, infection, and reduced range of motion. These difficulties often go unrecognized and untreated.
It's the Law
Recent DEA Developments

E-prescribing of controlled substances and prescription misuse are among the many issues being addressed by the Drug Enforcement Administration.
Clinical Corner
Photo Review of Selected NMEs 2012

Six new molecular entities (aflibercept, asparaginase Erwinia chrysanthemi, brentuximab vedotin, glucarpidase, ipilimumab, lucinactant) that were recently approved by the FDA are discussed.
Photo Management of Nerve Injuries

Trauma to nerves causes considerable loss of function in many individuals. Neuronal death due to trauma is an important clinical issue.
Consult Your Pharmacist
Preventing Caries and Gingivitis

Pharmacists can offer consumers valuable advice about how to avoid these common oral health problems.
Educational Spotlight
Special Considerations for the Treatment of HIV in Women

Antiretroviral therapy plays an integral role in preventing perinatal transmission of the disease.
Update on the Treatment and Prevention of MRSA Infections

Pharmacists can help develop programs to improve outcomes, halt antimicrobial resistance, and reduce adverse events.
Emphysema: A Clinical Review

Current guidelines do not differentiate between emphysema and chronic bronchitis, but collectively address treatment under the heading of COPD.
NASA and Epiomed to Develop Motion Sickness Spray
Houston, TX, and Irvine, CA — NASA's Johnson Space Center (JSC) and Epiomed Therapeutics, Inc., have signed an agreement to develop and commercialize a NASA-crafted, fast-acting nasal spray for motion sickness. NASA has extensively researched treatments for the condition, which often afflicts astronauts in space. With a precise dosage, the spray formulation—intranasal scopolamine (INSCOP)—works faster and more reliably than the oral form. Epiomed will formulate the drug. "NASA and Epiomed will work closely together on further development of INSCOP to optimize therapeutic efficiency for both acute and chronic treatment of motion sickness," stated Lakshmi Putcha of JSC. The drug will be made available to land, air, and sea travelers, in addition to being used by NASA and the Department of Defense.
Another Potential Use for Botox
Los Angeles, CA — According to a study conducted at the University of California, Los Angeles, Botulinum toxin type A (Botox) injections significantly improve pain and quality of life in patients with chronic bilateral posterior neck and shoulder myofascial pain syndrome (MPS). Botox, a neurotoxin that blocks nerve signals responsible for muscle tightening, is used to treat various painful disorders, including migraine, spasticity, and cervical dystonia. Subjects who received Botox injections had significantly greater reductions in pain scores, number and severity of headaches, and interference of pain with general activity, sleep, and enjoyment versus subjects given placebo. Botox may be an option for MPS patients whose pain is not relieved with traditional therapies.
Antibiotic Resistance a Concern With UTIs
Corvallis, OR — Concerns over antibiotic resistance are causing U.S. physicians to increasingly prescribe newer, more powerful antibiotics to treat urinary tract infections (UTIs). This practice, however, is raising its own concerns. Researchers at Oregon State University (OSU) suggest that these stronger drugs are being used more frequently than necessary. Overuse of the most potent drugs, including quinolones, hastens the development of bacterial resistance. "Because of higher levels of antibiotic resistance to older drugs in some regions, some doctors are now starting with what should be their second choice of antibiotic," noted Jessina McGregor, assistant professor of pharmacy at OSU and expert in the development of drug resistance. Older, more targeted drugs are effective for treating UTIs and should be considered before more powerful antibiotics.
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