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Issue:  February 2013 •  Archive  •  Subscribe •  Unsubscribe
In This Edition Featured Article Featured CE
•  Editor's Notebook
•  Counseling Pearls
•  It's the Law
•  Clinical Corner
•  Consult Your Pharmacist
•  Educational Spotlight
•  Quick Poll
  – Counseling Reimbursement
  Photo Antiarrhythmic Therapy for Atrial Fibrillation
Class IC and III agents are commonly used to maintain normal sinus rhythm.
  Photo The Role of the Pharmacist in Managing Hyperlipidemia
Pharmacists can help improve patient adherence to lipid-lowering therapies.

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Editor's Notebook
Why Is It Taking So Long?

The private sector has been slow to adopt health care models that give pharmacists an expanded role.
Counseling Pearls
Photo The Pathophysiology and Treatment of Stable Angina Pectoris

This condition is the most common manifestation of myocardial ischemia. Symptoms, which are caused by exertion and emotional stress, are relieved with sublingual nitroglycerin.
Photo Diabetes and Sudden Cardiac Death

Diabetes is associated with this event, but whether it is a specific risk factor is unknown. Although it is recognized as a clinical risk marker, it is not currently used for risk stratification.
It's the Law
Insider Trading and Clinical Trials

In history’s largest insider-trading case, a doctor disclosed drug trial results to a hedge fund.
Clinical Corner
Photo Acute Decompensated Heart Failure

This disorder can result from poorly controlled, chronic heart failure and/or cardiac, pulmonary, or renal dysfunction. Discharge support and rapid postdischarge follow-up are important.
Photo Cardiac Asthma: Not Your Typical Asthma

Because of similar symptoms, this condition is often misdiagnosed as bronchial asthma. Accurate diagnosis is imperative because incorrect treatment can exacerbate the disorder.
Consult Your Pharmacist
Benefits and Risks of Daily Aspirin Use

Patients should consult their physician before taking aspirin to prevent stroke and heart attack.
Educational Spotlight
Identification, Prevention, and Treatment Recommendations for Concussions

Sports-related head injuries are being increasingly discussed in an attempt to raise awareness of the severity of complications relating to concussions.
A Pharmacist-Only Class of Drugs: An Idea Whose Time Has Come?

There are pros and cons to implementing a behind-the-counter drug class, an idea currently under FDA consideration.
Cultural Competence in Behavioral Health Care

Those involved in the delivery of behavioral health care must be ready to address the cultural factors and health perceptions that can affect care.
Untreated Depression and Shingles Vaccine Response May Be Linked
Los Angeles, CA — A longitudinal cohort study of 40 subjects aged 60 years and older with major depressive disorder and 52 age- and gender-matched healthy controls suggests a link between untreated depression in older adults and reduced shingles (herpes zoster) vaccine effectiveness. Immune response was measured before administration of zoster vaccine or placebo and at 6 weeks, 1 year, and 2 years afterward. Compared with nondepressed controls and depressed subjects treated with antidepressants, depressed subjects not being treated with antidepressants had lower cell-mediated immunity to the varicella-zoster virus and had a poorer response to the shingles vaccine. Treatment of depression appeared to normalize subjects’ immune response to the vaccine.
African American Women Don’t Need Larger Vitamin D Doses
Omaha, NE— According to a recent double-blind study, African American women with vitamin D deficiency should take the same dose that white women take to treat the condition. In the study, older African American and white women of similar body size responded identically to vitamin D supplementation of varying doses, even though women with darker skin tones tend to have lower levels of the biomarker used to measure vitamin D levels (25OHD). Levels of 25OHD were similar between groups, suggesting that vitamin D absorption and metabolism are the same in African American and white women. It was concluded that lower levels of serum 25OHD in African Americans must be due to lower production of vitamin D in the skin.
Probiotics Could Prevent NEC in Premature Babies
Boston, MA — Chemicals secreted by good bacteria typically living in babies’ intestines could reduce the frequency and severity of necrotizing enterocolitis (NEC), a serious disease of premature infants. Researchers grew probiotic strains of Lactobacillus acidophilus and Bifidobacterium infantis and exposed fetal intestinal tissue and intestinal tissue from infants with NEC to secretions from the probiotic conditioned medium (PCM). PCM treatment was found to significantly reduce inflammation in both types of tissue. Secretions from B infantis showed a greater ability to reduce inflammation than those from L acidophilus, although this finding does not rule out the possibility of a synergistic effect when used together. If purified secretions can reduce NEC’s incidence and severity, this may ultimately change the standard of care for very-low-birthweight infants.
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