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Issue:  August 2013 •  Archive  •  Subscribe •  Unsubscribe
In This Edition Featured Article Featured CE
•  Editor's Notebook
•  Counseling Pearls
•  Senior Care
•  Clinical Corner
•  Consult Your Pharmacist
•  Educational Spotlight
•  Quick Poll
  – E-Prescribing
  Photo Managing Iron Deficiency Anemia of CKD With IV Iron
This prevalent complication of chronic kidney disease is underdiagnosed and undertreated, particularly in dialysis patients.
  Photo Screening and Management of Diabetic Kidney Disease
Early recognition and diagnosis of this microvascular complication of diabetes can reduce morbidity and mortality.
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Editor's Notebook
A Familiar Health Care Model

Data support pharmacists’ value in improving health care outcomes and lowering costs.
Counseling Pearls
Photo Catheterization and Urostomy for the Community Pharmacist

Detailed knowledge of processes and products is important, given the number of these procedures being performed. Traditionally, there has been a lack of pharmacist education on these topics.
Photo Treating Uncomplicated Cystitis

This bladder infection can be managed with prescription medications, as well as nonprescription strategies. Despite the number of antimicrobials available, incidence and recurrence remain high.
Senior Care
Nephrotic Syndrome: Medication and Other Related Risks

Since generalized edema is the major clinical manifestation of this condition, it is often misdiagnosed as congestive heart failure in geriatric patients.
Clinical Corner
Photo The Role of Pharmacists in the Management of Acute Kidney Stones

The lifetime prevalence of at least one kidney stone is up to 12% in males and 7% in females. Acute management involves a combination of supportive care and pharmacotherapy.
Photo Understanding Uremia

In this syndrome, several biochemical and physiological mechanisms associated with deteriorating renal function are impaired. Symptoms are nonspecific and difficult to identify in early disease.
Consult Your Pharmacist
A New Nonprescription Product for Overactive Bladder in Women

Approval of this transdermal system means that, for the first time, an OTC product may be purchased for this condition.
Educational Spotlight
Community-Acquired Bacterial Pneumonia: A Primer for Pharmacists

CABP is the most frequently occurring infectious disease in the U.S.
Strategies for the Prevention and Management of Nevi (Moles)

The presence of multiple moles is associated with an increased risk of melanoma.
Recognizing and Treating Tonsillitis

Penicillin is considered the gold standard of therapy for this common childhood condition.
Possible Permanent Nerve Damage From Fluoroquinolones
Silver Spring, MD — The FDA has warned that fluoroquinolones can potentially cause peripheral neuropathy, and that the nerve damage may last for months or years—or even be permanent—after discontinuation. Accordingly, the FDA is requiring that drug labels and medication guides for all fluoroquinolone antibacterial drugs be updated to better describe this serious side effect. The nerve damage, which occurs only with oral and injectable forms, may develop soon after these drugs are taken. If a patient develops symptoms of peripheral neuropathy, the fluoroquinolone should be discontinued and the patient switched to a nonfluoroquinolone antibacterial drug, unless the benefit of continued fluoroquinolone treatment outweighs the risk. The FDA will continue to investigate the safety of drugs in the fluoroquinolone class.
Optimal Dosing for Elderly Heart Patients Explored
Durham, NC— Researchers at Duke Medicine, in examining a substudy of a large clinical trial comparing prasugrel with clopidogrel for management of acute coronary syndromes, have determined that in certain heart patients aged >75 years, a half-dose of the antiplatelet drug prasugrel works as well as the standard dose of clopidogrel. These patients are highly vulnerable to bleeding and other side effects if therapies are dosed improperly. In the analysis, which included more than 2,000 elderly patients, a smaller dosage of prasugrel (5 mg daily) presented no greater risk of bleeding than the commonly used 75-mg dosage of clopidogrel. Dedicated studies are necessary to further clarify the appropriate use of anticlotting agents in elderly patients.
Even Without Diabetes, Higher Blood Sugar Tied to Dementia Risk
Seattle, WA— Higher blood sugar levels are associated with a higher risk of dementia, even in nondiabetic patients. In more than 2,000 patients aged ≥65 years from the longitudinal cohort study Adult Changes in Thought, blood sugar levels averaged over 5 years were associated with a rising risk of developing dementia. In patients with diabetes, the dementia risk was 40% higher in those with a mean glucose level of 190 mg/dL versus those with a mean level of 160 mg/dL. In nondiabetic patients, the risk was 18% higher in those with a mean level of 115 mg/dL versus those with a mean level of 100 mg/dL. It was not determined whether making modifications to lower one’s glucose level improves one’s dementia risk.
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