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Issue:  October 2013 •  Archive  •  Subscribe •  Unsubscribe
In This Edition Featured Article Featured CE
•  Editor's Notebook
•  Counseling Pearls
•  It's the Law
•  Clinical Corner
•  Consult Your Pharmacist
•  Educational Spotlight
•  Quick Poll
    – Foreign Drug Imports
  Photo New Drug Review 2013
This article reviews five new drugs that were approved by the FDA in the past year.
  Photo Drug Rescheduling and Controlled Substances
Federal and state lists of controlled substances and dispensing restrictions continue to evolve.
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Editor's Notebook
The Yin and Yang of Pharmacy

In pharmacy, the delicate balance between business and profession must be maintained.
Counseling Pearls
Photo Legislative Initiatives and Review of Abuse-Deterrent Opioid Formulations

Many states have amended laws to allow access to emergency care and treatment of overdose, and the pharmaceutical industry is developing delivery systems resistant to abuse and diversion.
Photo Update on Pharmacotherapeutic Options for Rheumatoid Arthritis

Newer drugs are among the biologic agents used to manage this autoimmune disease. Despite major advances in treatment, the main etiology remains unknown.
It's the Law
Lethal Injections, Drug Shortages, and Pharmacy Ethics

Recent shortages of drugs used for the death penalty further complicate this controversial issue.
Clinical Corner
Photo SGLT2 Inhibitors: A Review of Canagliflozin

This novel drug is an alternative for type 2 diabetes patients not well controlled on current therapy or diet and exercise. It increases glucose excretion by inhibiting sodium-glucose co-transporter 2 in the kidney.
Photo Drug Interactions Associated With Pulmonary Arterial Hypertension Therapy

Combination therapy may be beneficial, but drug interactions can occur. Specialized knowledge about these agents allows pharmacists to perform drug monitoring, thus preventing adverse events.
Consult Your Pharmacist
Blood Glucose Meters

Self-monitoring of blood glucose is an important part of modern therapy for diabetes mellitus.
Educational Spotlight
Pharmacogenomics in Women's Health

Relating genetics to drug response is the basis of this rapidly expanding field.
Screening and Management of Diabetic Kidney Disease

Early recognition and diagnosis of this microvascular complication of diabetes can reduce morbidity and mortality.
Community-Acquired Bacterial Pneumonia: A Primer for Pharmacists

CABP is the most frequently occurring infectious disease in the U.S.
Low Vitamin D Levels Increase Risk of Anemia in Children
Baltimore, MD — Research from Johns Hopkins Children's Center indicates that low levels of vitamin D increase a child's risk of anemia. According to researchers, the results provide evidence of a complex interplay between low vitamin D levels and hemoglobin. Among the possible mechanisms are the vitamin's effects on RBC production in bone marrow and its ability to regulate immune inflammation. In blood samples from more than 10,400 children, vitamin D levels were consistently lower in children with low hemoglobin levels compared with nonanemic children. Levels below 30 ng/mL conferred nearly twice the anemia risk versus normal levels. Senior researcher Jeffrey Fadrowski, MD, MHS, noted that low vitamin D levels may be "a readily modifiable risk factor" that can be handled with supplementation.
Menopausal Hot Flashes Improved With Chronic Pain Treatment
Chicago, IL— Menopausal women experience half as many hot flashes after receiving a chronic pain treatment, according to investigators at Northwestern University Feinberg School of Medicine. The nerve block treatment interrupts the part of the brain that regulates temperature, reducing moderate-to-severe hot flashes and alleviating depression. Of 40 patients aged 30 to 65 years with at least 25 hot flashes per week, 20 received a stellate ganglion injection with a local anesthetic, and the rest received placebo. All patients recorded their daily number of hot flashes and were followed for 6 months. Besides the 50% improvement in hot flashes in treated patients, there was a 30% decrease in depression and a 10% improvement in verbal learning.
Resveratrol Could Help Treat a Variety of Cancer Types
Columbia, MO— A study conducted at the University of Missouri (MU) found that resveratrol, a compound in grapes and red wine, can render certain tumor cells more susceptible to radiation. The study, which examined how resveratrol and radiation inhibited the survival of melanoma cells, was preceded by an MU study of the compound that found similar results for prostate cancer. Melanoma cells were more susceptible to radiation after resveratrol treatment. Sixty-five percent of melanoma cells treated with resveratrol plus radiation died, versus 44% of melanoma cells treated with resveratrol alone. The next step is to develop a successful method for delivering the compound to tumor sites and potentially treat many types of cancer.
To subscribe to e-Connect, send your name, address, and email address to us by clicking here. U.S. Pharmacist is a monthly journal dedicated to providing the nation's pharmacists with up-to-date, authoritative, peer-reviewed clinical articles relevant to contemporary pharmacy practice in a variety of settings, including community pharmacy, hospitals, managed care systems, ambulatory care clinics, home care organizations, long-term care facilities, industry and academia. The publication is also useful to pharmacy technicians, students, other health professionals and individuals interested in health management. Pharmacists licensed in the U.S. can earn Continuing Education credits through Postgraduate Healthcare Education, LLC, accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education.