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Issue:  December 2013 •  Archive  •  Subscribe •  Unsubscribe
In This Edition Featured Article Featured CE
•  Editor's Notebook
•  Counseling Pearls
•  It's the Law
•  Clinical Corner
•  Consult Your Pharmacist
•  Educational Spotlight
•  Quick Poll
    – Statin Guidelines
  Photo An Outpatient Approach to Nausea and Vomiting
Prevention and treatment rely upon the precipitating mechanisms from which the condition results.
  Photo The Clinical Management of Gastroesophageal Reflux Disease
Lifestyle modifications and pharmacotherapy are important components of GERD management.
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Editor's Notebook
The Other "O"-pidemic

If you suspect that a colleague is addicted to opioids, notify someone who can provide immediate help.
Counseling Pearls
Photo Bowel Preparations: A Review for Community Pharmacists

To maximize the diagnostic accuracy of colonoscopy, the patient must be prepared for the procedure. Two factors that limit the success of colonoscopy preparations are patient compliance and tolerability.
Photo Long-Term Consequences of Chronic Proton Pump Inhibitor Use

PPIs are commonly used for the treatment of acid-related disorders. Continued use of these agents, however, can potentially result in malabsorption problems and an increased risk of infections.
It's the Law
Time Matters: Statute of Limitations

The time between an injury caused by a pharmaceutical mistake and the filing of a lawsuit is often crucial.
Clinical Corner
Photo Carbapenem-Resistant Enterobacteriaceae: An Emerging Threat

Limited treatments and a high mortality rate render CRE infection a growing threat. Exposure to antimicrobial therapy and the healthcare environment are strongly associated with transmission.
Photo Antibiotic Therapy for Appendicitis in Children

The choice of treatment depends upon the severity of the presentation as well as the patient's general condition. Appropriate IV antibiotics should be initiated upon diagnosis and postappendectomy.
Consult Your Pharmacist
Counseling Patients About Constipation

Factors to consider include patient age, current medications, and laxative misuse or abuse.
Educational Spotlight
Issues and Data Associated With Addictive Disease in Pharmacists

Pharmacies can present a precarious environment for the development of addiction.
Drug Rescheduling and Controlled Substances

Federal and state lists of controlled substances and dispensing restrictions continue to evolve.
Pharmacogenomics in Women's Health

Relating genetics to drug response is the basis of this rapidly expanding field.
Narrow-Spectrum Antibiotics Effective for Childhood Pneumonia
Nashville, TN — A study by Vanderbilt University concluded that children hospitalized for pneumonia have similar outcomes whether they are treated with narrow-spectrum antibiotics, such as penicillin and ampicillin, or broad-spectrum antibiotics, such as cefotaxime and ceftriaxone. Data from 43 children's hospitals on children aged 6 months to 18 years who were hospitalized for pneumonia from 2005 to 2011 were analyzed. Ten percent of children received narrow-spectrum therapy, and about 90% received broad-spectrum therapy. There were no significant differences in clinical outcomes or associated costs between the two treatment regimens. These findings are important because pneumonia is one of the most common reasons for hospitalization in U.S. children and because broad-spectrum antibiotics are often overprescribed, resulting in antibiotic resistance.
Exercise Alleviates Antidepressants' Sexual Side Effects in Women
Austin, TX— Engaging in exercise just prior to sexual intercourse significantly improves sexual functioning in women taking antidepressants, according to a University of Texas study. Antidepressants interfere with the sympathetic nervous system (SNS), which facilitates blood flow to the genital region, but moderately intense exercise activates the SNS. In the study, which recruited 52 women with reported sexual side effects from antidepressants, subjects who performed 30 minutes of moderately intense exercise immediately before intercourse experienced significantly stronger libidos and overall improvements in sexual functioning. Committing to a regular exercise routine yielded improvements in all subjects, but the amount and timing of the exercise significantly influenced the level of improvement.
FDA Examining Antibacterial Soap More Closely
Silver Spring, MD— Based on the lack of evidence that OTC antibacterial soap products prevent illness more effectively than soap and water, the FDA has issued a proposed rule requiring manufacturers of antibacterial soaps to provide more substantial data demonstrating their safety and efficacy compared with washing with soap and water. Antibacterial soaps contain chemicals such as triclosan and triclocarban, which may carry unnecessary risks. There are indications that these ingredients may contribute to bacterial resistance to antibiotics and also may have unanticipated hormonal effects. These concerns warrant further investigation, according to the FDA. The proposed rule does not apply to hand sanitizers, hand wipes, or antibacterial soaps used in healthcare setting such as hospitals.
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