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Issue:  February 2014 •  Archive  •  Subscribe •  Unsubscribe
In This Edition Featured Article Featured CE
•  Editor's Notebook
•  Counseling Pearls
•  It's the Law
•  Clinical Corner
•  Consult Your Pharmacist
•  Educational Spotlight
•  Quick Poll
    – Cigarettes
  Photo Pediatric Hypertension
An estimated 3% to 5% of children have high blood pressure, and the incidence is rising.
  Photo Review of Coronary Artery Bypass Grafting
Many medications and lifestyle changes are indicated for patients who undergo this procedure.

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Editor's Notebook
Pot of Green for Pharmacists

Marijuana should be clinically tested if it is to be approved by federal law.
Counseling Pearls
Photo Metabolic Syndrome: Risk Factors and Recommendations

Patients with this disorder are at risk for cardiovascular diseases and diabetes. Because most components of metabolic syndrome have no associated symptoms, pharmacist intervention is important.
Photo Senior Care—Mechanical Heart Valves: Contraindication for Dabigatran Therapy

Aging can cause weak or stenotic valves. Dabigatran is more problematic than warfarin regarding side effects in patients with mechanical heart valves.
It's the Law
New Rules for Compounding Drug Products

The New England Compounding Center meningitis outbreak inspired the Drug Quality and Security Act.
Clinical Corner
Photo The Cardiotoxicity of Cancer-Related Drug Therapies

Heart damage is a prominent morbidity in patients surviving 5 to 10 years after therapy. Cardiotoxicity may lead to increased mortality and disease progression because of suboptimal therapeutic options.
Photo Cardiac Catheterization: A Review for Pharmacists

Pharmacotherapy plays a key role before, during, and after this procedure. Pharmacists should be aware of the benefits and risks of cardiac catheterization and the associated drug therapy.
Consult Your Pharmacist
The Link Between Periodontitis and Cardiovascular Disease

Pharmacists can recommend dental intervention and appropriate products to patients.
Educational Spotlight
Current Pharmacologic and Complementary Therapies for Tourette Syndrome

This neurologic disorder is characterized by uncontrolled motor and vocaltics
The Clinical Management of Gastroesophageal Reflux Disease

Lifestyle modifications and pharmacotherapy are important components of GERD management.
Issues and Data Associated With Addictive Disease in Pharmacists

Pharmacies can present a precarious environment for the development of addiction.
Vitamin D3 as Add-on Therapy Improves Relief From Hives
Omaha, NE — Adding vitamin D3 to allergy medications may provide relief from chronic hives, a condition with limited treatment options. In a small 2-year study, researchers at the University of Nebraska Medical Center treated 38 participants for 12 weeks with a combination of one prescription and two OTC allergy medications, and added an OTC vitamin D3 supplement. One-half of participants received 600 IU of vitamin D3; the rest received 4,000 IU. In all participants, hive severity diminished by 33% after 1 week. After 3 months, participants taking the higher dosage of D3 showed a further 40% reduction in severity, but the lower-dose group did not. Researchers concluded that vitamin D3 holds promise for treatment of chronic hives, with no adverse effects.
Cytokines Are Culprit for Pigment Changes in Psoriasis
New York, NY— Investigators at The Rockefeller University made a surprising discovery that may pave the way for treatment of pigmentation changes that can occur after flare-ups of not only psoriasis, but also eczema and acne. The two cytokines that are overexpressed in psoriasis—interleukin-17 and tumor necrosis factor—were found to play a role in post-outbreak pigment changes in addition to their known role in the outbreak itself. Psoriasis lesions with high levels of these cytokines also had more melanocytes than are typically found in noncancerous skin, a phenomenon previously thought to occur only in early melanocytic tumors, such as melanomas. The investigators expect this insight to impact the design of future therapies for skin disorders.
ICU Care Questioned for Some Stroke Patients Receiving tPA
Baltimore, MD— Patients hospitalized with ischemic stroke who have received a tissue plasminogen activator (tPA) infusion may not need the 24-hour critical-care monitoring that is the current standard, according to a recent study. Researchers analyzed data on 153 stroke patients admitted to emergency departments at two Johns Hopkins hospitals and found that patients who received a score of less than 10 on the National Institutes of Health Stroke Scale and did not need to be transferred to ICU after the first hour had a 1% risk of later developing a problem that would require ICU care. The researchers plan a prospective study to verify these results, cautioning that under certain circumstances, such as tPA-linked bleeding, ICU care is definitely necessary.
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