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Issue:  March 2014 •  Archive  •  Subscribe •  Unsubscribe
In This Edition Featured Article Featured CE
•  Editor's Notebook
•  Counseling Pearls
•  TechRx
•  Clinical Corner
•  Consult Your Pharmacist
•  Educational Spotlight
•  Quick Poll
    – Zohydro ER
  Photo Identifying and Treating Migraines in Children
Chronic headaches are often misdiagnosed in the pediatric population.
  Photo Drug-Drug Interactions Involving Pain Medications
Pharmacists need to be aware of analgesic drug interactions in order to optimize therapy.

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Editor's Notebook
A Healthy Decision

CVS should be praised for its decision to eliminate cigarettes and other tobacco products from its merchandising mix, but will other pharmacies follow their lead?
Counseling Pearls
Photo Cardiovascular Risk Associated With NSAIDs and COX-2 Inhibitors

Patients who have cardiovascular disease and are taking NSAIDs, especially COX-2 selective agents, are at a much higher risk of myocardial infarction than patients not taking these drugs. Therefore, understanding the potential danger of the use of NSAIDs in patients who have cardiovascular risk factors is essential.
Photo Overview of Adult Outpatient Cancer Pain Management

Cancer pain is one of the most difficult supportive care issues to manage, as it is subjective. Many physicians struggle with outpatient management of cancer pain in adults, and pharmacists can play a key role in recommending agents, titration, and conversions.
Electromedical Modalities in Pain Management

Pain specialists can now prescribe treatments that attack moderate-to-severe chronic pain using targeted techniques, such as spinal cord stimulators, electroanalgesic delivery systems, and pulsed radiofrequency therapies.
Clinical Corner
Photo Acetaminophen Toxicity: What Pharmacists Need to Know

Acetaminophen toxicity is one of the most common causes of unintentional poisoning and acute liver failure in the United States. The FDA has long been updating its recommendations regarding acetaminophen use to help improve patient safety.
Photo Epidural Anesthesia During Labor and Delivery

Epidural anesthetics are the most popular form of pain management currently chosen by the patient during labor. A number of anesthetics with varying properties are available in the U.S., and these agents must be carefully administered by a qualified professional in order to minimize complications.
Consult Your Pharmacist
Safe Self-Treatment of Headaches

There are several types of headache that are not due to any serious underlying cause, and patients may self-treat them. They include migraine (diagnosed by a doctor), tension headache, and cluster headache.
Educational Spotlight
Review of Coronary Artery Bypass Grafting

Many medications and lifestyle changes are indicated for patients who undergo this procedure.
Current Pharmacologic and Complementary Therapies for Tourette Syndrome

This neurologic disorder is characterized by uncontrolled motor and vocaltics
The Clinical Management of Gastroesophageal Reflux Disease

Lifestyle modifications and pharmacotherapy are important components of GERD management.
Statin May Slow Progression of Multiple Sclerosis
London, UK — Results of a phase II study published in The Lancet suggest that simvastatin, a generic cholesterol-lowering drug, might be a potential treatment option for the secondary progressive, or chronic, stage of multiple sclerosis (MS), which is currently untreatable. Findings from the MS-STAT trial showed that a high, daily dose (80 mg) of simvastatin was safe, well tolerated, and slowed brain atrophy (shrinkage) by 43% over 2 years compared with placebo. Longitudinal studies suggest that atrophy progression is linked with disability. To date, no licensed drugs have shown a convincing impact on this later stage of the disease. Further phase III studies will be required to measure the effect of simvastatin on sustained disability in patients with MS.
U.S. Tuberculosis Rates at Record Low
Atlanta, GA— According to the CDC, the number of tuberculosis (TB) cases in the United States has hit a record low, with fewer than 10,000 cases reported last year. In 2013, a total of 9,588 new TB cases were reported, with an incidence rate of 3.0 cases per 100,000 population, a decrease of 4.2% from 2012. Despite strict screening policies, immigrants are still 13 times more likely to be diagnosed with TB than native-born Americans. Four states (California, Texas, New York, Florida) accounted for approximately half of the reported cases. Multidrug-resistant TB remains unusual in the U.S., with only 86 cases in 2012, but is still a concern because it is difficult and expensive to treat and more often fatal.
HPV Test May Replace Annual Pap
Silver Spring, MD— Expert advisors to the FDA have recommended that a new screening test for the human papillomavirus (HPV) could replace the annual Pap smear for many women. They advise that the FDA should allow the test to be marketed as a first-line screening tool for cervical cancer, which causes more than 3,000 deaths annually. Only women with evidence of active HPV infection would then be given a Pap test, which is examined for evidence of cancerous or precancerous cells. HPV is very common and causes not only cervical cancer but cancer of the mouth, throat, penis, and other areas. "If approved, the cobas HPV Test would become the first and only HPV test indicated as the first-line primary screen of cervical cancer in the U.S." a representative from Roche, the test's manufacturer, stated.
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