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Issue:  April 2014 •  Archive  •  Subscribe •  Unsubscribe
In This Edition Featured Article Featured CE
•  Editor's Notebook
•  Counseling Pearls
•  Senior Care
•  Clinical Corner
•  Consult Your Pharmacist
•  Educational Spotlight
•  Quick Poll
    – BP Guidelines
  Photo Acute Pericarditis Treatment: Update on Colchicine
This agent has the ability to disrupt the inflammatory cycle involved in pathogenesis.
  Photo Influenza Vaccine in Children and Adults With Egg Allergy
Mild egg allergy is no longer listed as a contraindication to receiving the influenza vaccine.
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Editor's Notebook
Getting No Respect Is Not a Joke

A new bill would enable pharmacists to be recognized as providers under Medicare Part B.
Counseling Pearls
Photo Pneumococcal Vaccination: Optimizing Preventive Strategies and Reducing Disease Burden

Pneumococcal disease is a concern in very young, elderly, and immunocompromised populations. There are two commercially available vaccines for prevention—Pneumovax 23 and Prevnar 13.
Photo Treating Prostatitis Effectively: A Challenge for Clinicians

Most physicians are unfamiliar with the disorder, particularly chronic prostatitis associated with chronic pelvic pain syndrome. Clinical pharmacists can help develop individualized treatment regimens.
Senior Care
Hepatitis C Alert: Baby Boomers Should Be Tested

Testing, early diagnosis, and treatment can prevent liver damage and diseases.
 
Clinical Corner
Photo Management of Occupational Exposure to HIV

More than 5 million workers are at risk for occupational exposure to bloodborne pathogens, including HIV. Guidelines for management and postexposure prophylaxis were recently released.
Photo Viral Meningitis: An Overview

This infection, which is responsible for one-half of U.S. meningitis hospitalizations, is usually self-limiting. It is the most common form of meningitis, and individuals of all ages can develop it.
 
Consult Your Pharmacist
Advising Patients About Sinus Infections

Instead of self-treating, patients must visit a physician for a differential diagnosis.
 
Educational Spotlight
Drug-Drug Interactions Involving Pain Medications

Pharmacists need to be aware of analgesic drug interactions in order to optimize therapy.
Review of Coronary Artery Bypass Grafting

Many medications and lifestyle changes are indicated for patients who undergo this procedure.
Current Pharmacologic and Complementary Therapies for Tourette Syndrome

This neurologic disorder is characterized by uncontrolled motor and vocal tics.
 
Newswire
New Combination Drug Therapy Promising for HCV
Boston, MA—A new 12-week single-tablet regimen of ledipasvir and sofosbuvir has been proven highly effective in treating a wide swath of patients with hepatitis C virus (HCV) genotype 1, which is found in up to 75% of HCV infections. In two multicenter trials conducted by researchers from Beth Israel Deaconess Medical Center, between 94% and 99% of patients were cured of HCV. Results were similar between patients never treated and those previously treated with the standard course of peginterferon and ribavirin, and the oral regimen was also better tolerated. "[The] tablet enables us to treat almost all genotype 1 patients with a short duration of treatment, expanding the treatment pool and increasing the overall cure rate," noted senior author Nezam Adfhal, MD.
Sleep Apnea Confers Higher Risk of Stroke, Cancer, and Death
Sydney, Australia—A 20-year follow-up study from the University of Sydney has found an independent association between moderate-to-severe obstructive sleep apnea (OSA) and increased risk of stroke, cancer, and mortality. Subjects with a history of stroke or cancer were excluded from analysis. Participants with moderate-to-severe OSA were four times more likely to die, nearly four times more likely to have a stroke, and 2.5 times more likely to develop cancer. During follow-up, 77 deaths and 31 strokes occurred, as well as 125 cancer events (39 of them fatalities). Mild OSA was not associated with increased health risks. Results of this study are consistent with findings from earlier research conducted in the United States and Spain.
Prenatal SSRI Use Linked to Autism, Developmental Delays in Boys
Baltimore, MD—A large study found an association between prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) and autism spectrum disorder (ASD) and developmental delays (DD) in boys. Researchers from Johns Hopkins Bloomberg School of Public Health analyzed data on 966 mother-child pairs from a large population-based case-control study in which ASD and DD diagnoses were confirmed by trained clinicians using validated standardized instruments. Boys constituted 82.5% of the ASD group and 65.6% of the DD group. In boys, first-trimester exposure to SSRIs was linked to ASD, whereas third-trimester exposure was associated with DD. The substantially stronger association in boys versus girls suggests possible gender differences in the effect of prenatal SSRI exposure.
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