Nociceptive and neuropathic pain rise from complex interations between neurological pathways in the spinal cord and brain, and modulation of both ascending and descending pathways involved in transmission and inhibition of pain signalling may provide effective analgesia for many patients.
Intravenous chemotherapeutic medications have the potential to cause
extravasation injury or tissue necrosis at the site of administration.
Mantle cell lymphoma is an aggressive disease that carries an unfavorable prognosis.