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Scleroderma: Managing Systemic Sclerosis and Its Complications

The treatment of systemic sclerosis and its complications is complex and requires careful evaluation and collaboration between the pharmacist and other practitioners.

Alzheimer’s Drug Development Suspended



Nicotine Patch May Help Improve Memory



Identifying Drug-Induced Lupus

Chronic use of certain drugs can cause this rheumatologic syndrome

Neurologic Complications of HIV

Despite the availability of effective antiretroviral therapy, more than 25% of people with HIV infection will develop neurologic disorders.

GASTROENTEROLOGY

GERD-Related Sleep Disturbances 1/20/2012

Sleep disturbance is a common complaint in patients suffering from GERD

Acute Pancreatitis: Risks, Causes, and Mortality in Older Adults 12/20/2011

In the elderly, acute pancreatitis is most commonly caused by gallstones, is more likely to be severe, and is associated with higher mortality. 



Approach to Treatment and Prevention of Traveler’s Diarrhea 12/20/2011

Millions of travelers are affected by traveler's diarrhea annually, so it is vital that pharmacists proactively educate individuals who will be traveling about preventive measures and treatment.

Counseling Patients With Hemorrhoids 12/20/2011

Many patients who initially seek relief through the use of nonprescription products will require referral to a physician. 

Disorders Associated With Celiac Disease 12/20/2011

With celiac disease, the risk of developing other autoimmune and nonautoimmune disorders increases.

Evaluation of Strategies to Improve the Treatment of Recurrent Clostridium difficile–Associated Disease 12/20/2011

New methods for treating this common nosocomial infection are being implemented. 

Fructose Malabsorption: A Possible Factor in Functional Bowel Disorders 12/20/2011

Elimination of dietary fructose can have a positive effect on clinical symptoms. 

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GERD 12/20/2011

When stomach acid is refluxed into the esophagus over a long period of time, it is known as gastroesophageal reflux disease. 



Gluten-Free Cosmetics Difficult to Find 12/20/2011



Management of Gastroparesis 12/20/2011

Underlying conditions and comorbidities make it difficult to properly manage this disorder.



Pharmaceutical Care of Celiac Disease 12/20/2011

Celiac disease, also known as gluten-sensitive enteropathy or sprue, is a chronic autoimmune disorder caused by a genetic intolerance to gluten.

Hospital Superbug Deconstructed 11/16/2011



Stress Ulcer Prophylaxis: The Consequences of Overuse and Misuse 10/19/2011

It seems as though almost every patient admitted to the hospital in the United States is prescribed either a proton pump inhibitor or a histamine-2 antagonist as stress ulcer prophylaxis.

Bariatric Surgery for the Treatment of Type 2 Diabetes Mellitus: What Are the Options? 5/18/2011

Beyond weight management, these procedures may induce remission of T2DM. 

Heartburn Medications May Increase Pneumonia Risk 1/20/2011



Diarrhea: How to Assist the Patient 12/17/2010

This disorder requires more counseling than other conditions treatable by self-care. 

Direct Costs for Treatment of Digestive Diseases 12/17/2010

According to the National Institutes of Health, 60 to 70 million people suffered from digestive diseases in 2004.

Gallstones: Aging and Medications Increase Risk 12/17/2010

About 50% to 70% of acute cholecystitis occurs in seniors; use of estrogen replacement therapy in post-menopausal women also increases risk.

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Lactose Intolerance 12/17/2010

People with this condition have trouble digesting milk sugar (lactose) due to a relative lack of the enzyme lactase.

Management of Diverticular Disease 12/17/2010

Older age and insufficient dietary fiber intake are the two biggest risk factors for diverticulosis and diverticulitis. 

Management of Nonvariceal Upper Gastrointestinal Bleeding 12/17/2010

Acute gastrointestinal bleeding is a common life-threatening medical emergency requiring hospital admission.

Overview of Peptic Ulcer Disease 12/17/2010

This disease encompasses gastric, duodenal, and esophageal ulcers, with common etiologies of Helicobacter pylori infection and NSAID use. 

Review of Current Chronic Constipation Guidelines 12/17/2010

Constipation accounts for approximately 2.7 million physician office visits, is responsible for an annual cost of about $8 billion per patient, and occurs in 12% to 19% of the U.S. population.

Treatment Options for Postoperative Ileus 12/17/2010

This condition frequently is a result of abdominal or nonabdominal surgery, but other causes include certain types of medications, inflammation, hematoma, and metabolic disturbances.

Ulcerative Colitis: Therapeutic Management Update 12/17/2010

A mix of immunologic, infectious, and genetic factors may be responsible for this form of inflammatory bowel disease. 

Name Change for Heartburn Drug 4/19/2010



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Crohn's Disease: Current Management and Prospective Therapies 1/20/2010

Crohn's disease is a chronic form of irritable bowel disease that can extend through the various layers of the gastrointestinal tract, resulting in intestinal and extraintestinal complications.

Colorectal Cancer Screening 12/17/2009

Routine examinations, beginning at age 50, are key to preventing this disease and saving lives.


Gastrointestinal Bleeding: An Alarming Sign 12/17/2009

Early intervention to control bleeding is important in order to minimize mortality, particularly in elderly patients.


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IBS Treatment Guidelines 12/17/2009

Irritable bowel syndrome places a significant burden on society; it also presents an excellent opportunity for pharmacists to participate in the care of patients with the disorder.

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Overview of Hepatitis B and C Management 12/17/2009

Pharmacists play an important role in the care of patients infected with these diseases, which often lead to chronic liver disease and even death

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Pancreatitis 12/17/2009

The pancreas produces insulin and enzymes that help digest food and can become inflamed as a result of alcoholism, gallstones, or infection.



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Probiotics and Microflora 12/17/2009

There is a new focus on the role of beneficial bacteria to aid digestion, boost natural defenses, and fight off bacteria that could cause health problems.


Strategies for the Relief of Bloating and Gas 12/17/2009

Various sources for this problem have been identified, including air swallowing, diet, lactose intolerance, and IBS.

The Burden of Digestive Diseases 12/17/2009

At the end of the 20th century, there were changes in the incidence, prevalence, and overall impact of digestive diseases, as evidenced by the 2008 update to the National Institutes of Health publication on digestive diseases.

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Updates in Nonprescription Therapy for Heartburn and GERD 10/21/2009

Understanding the relative advantages and disadvantages of OTC antacids, H2 antagonists, and proton pump inhibitors allows the pharmacist to provide lasting relief for patients.



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Alcohol-Induced Pancreatitis 8/20/2009

An association exists between alcohol abuse and pancreatitis, but the mechanism involved is not understood.


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The Relationship Between GERD and Asthma 7/20/2009

Health care providers should be aware that reflux symptoms are a potential trigger of respiratory distress.


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Adverse Events Associated with NSAIDs 12/15/2008

Nonsteroidal anti-inflammatory drugs (NSAIDs) and cyclooxygenase (COX)-2 inhibitors (COXIBs) are perhaps some of the most extensively used medications in the world.

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Ulcerative Colitis: Achieving and Maintaining Remission 12/15/2008

Ulcerative colitis (UC) is a chronic inflammatory bowel disorder (IBD) characterized by diffuse mucosal inflammation of the colon.

Diseases of the Digestive System 12/15/2008

A ccording to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), digestive diseases have affected more than 70 million Americans.

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The Operating Room Pharmacist and Bariatric Surgery 12/15/2008

According to the Centers for Disease Control and Prevention (CDC), the percentage of overweight or obese persons in the U.

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Celiac Disease: More Common Than Once Thought 12/15/2008

A n estimated one of every 100 to 200 people in the United States has celiac disease (also known as gluten-sensitive enteropathy, nontropical sprue, or celiac sprue), an autoimmune inflammatory enteropathy that is triggered by the ingestion of gluten-containing grains in susceptible individuals.

Understanding and Managing Lactose Intolerance 12/15/2008

The inability to ingest milk as an adult, known as lactose intolerance (LI) , is characteristic of many ethnic groups.

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Inguinal Hernia 8/14/2008

A hernia is a bulging of connective tissue (fascia) through a weak area or tear in the wall of muscle that holds the intestines in place.

Probiotics: A Closer Look 6/19/2008

Probiotics are dietry supplements that have been used for centuries as natural components in health-enhancing foods.

Diverticulitis: Overview and Management 3/20/2008

Some illnesses are found to take varied courses in geriatric patients.

Clinical News Digest 1/23/2008

FDA Says No Change in Cardio Risks for Prilosec and Nexium Earlier this year, AstraZeneca, the manufacturer of Prilosec (omeprazole) and Nexium (esomeprazole), sent the FDA results of studies being conducted by the pharmaceutical company on the long-term use of the two drugs.

GERD Update: The Refractory Patient 12/20/2007

Heartburn, one of the classic symptoms of gastroesophageal reflux disease (GERD), is a very common occurrence among the general population.

Bariatric Surgery 9/19/2007

For many individuals--especially those who are morbidly obese--diet and exercise, even in combination with drug therapy, are usually not enough to achieve adequate weight loss.

A Review on the Management of Crohn's Disease 1/23/2007

Inflammatory bowel disease (IBD) is a condition that causes chronic inflammation in the lining of the gastrointestinal tract (GIT).

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