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| December 2021 |
Does Insulin Resistance Result From the Body's Misguided Reward System?
Researchers from the German Center for Diabetes Research reported that an interaction between insulin and dopamine in the striatum region of the brain can alter the regulation of glucose metabolism and eating behaviors. The scientists determined that obesity leading to changes in brain's signaling can adversely impact glucose metabolism in the entire body. Read their results, published in the Journal of Clinical Endocrinology & Metabolism.
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Future Diabetes Treatments May Evolve From Unexpected, Nonhuman Sources
Medical researchers often employ the practice of synthesizing medications from chemicals found in nonhuman, living creatures, such as GLP-1 discovered in the saliva of Gila monsters that is now used to treat diabetes in humans. Emerging studies indicate that a specialized, insulin-like toxic protein used by snails to immobilize prey is a potential new diabetes treatment. Read more about these finding, published in Proteins: Structure, Function, and Bioinformatics.
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Avoiding Diabetic Intervention at Discharge Might Be Beneficial
Diabetes is a state of insulin resistance resulting from many known factors, such as poor diet, sedentary lifestyle, and obesity, but there are likely unknown causes, too. In research published in Cell Metabolism, scientists from the University of Connecticut explored some of these lesser known influences, including the physiologic impact of cellular senescence, which describes the outcome of stress on cells, including proinflammatory secretions. Read more.
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