April 2022

Real Effectiveness of Palbociclib Plus Fulvestrant in Advanced BC
Despite the great strides that have been made in the management of early breast cancer (BC), advanced-stage BC has a 3- and 5-year survival rate of only 35% to 55% and 25%, respectively. Investigators conducted a study to evaluate the effectiveness of palbociclib plus fulvestrant in the real-world clinical setting during the period of early access to palbociclib in patients with advanced BC. Read more.


Tramadol Effect on Survival in BC Patients
According to the CDC, it is estimated that about 20% of the U.S. population suffers from chronic pain. Compared with other demographic groups, chronic pain is highest among women, occurring in about 21.7%. Given that the lifetime risk of developing breast cancer (BC) in the U.S. is about 13%, the potential exists for women suffering from chronic pain to also develop BC. Read more.

Auricular Acupressure Beneficial for Chemotherapy-induced Nausea and Vomiting
Despite effective therapies such as the 5-HT3 receptor antagonists and NK1 receptor antagonists, chemotherapy-induced nausea and vomiting can often be difficult to manage. Therapies such as auricular acupressure (AA) may have a complementary role and may add to the beneficial effect of pharmacologic therapy. However, evidence on the effects of AA is inconclusive since many of these trials are plagued by methodological issues. Read more.

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