March 2021

Updated Guideline for Adjuvant Chemotherapy, Targeted Therapy in Early Breast Cancer
The American Society of Clinical Oncology, which develops and disseminates clinical practice guidelines and other guidance documents to assist providers in their clinical decision-making, recently published a focused update of its 2018 guidelines on the selection of optimal adjuvant chemotherapy and targeted therapy for early breast cancer. Read more.

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Do Beta-Blockers Have a Role in Early Breast Cancer?
Preliminary evidence from retrospective studies indicates a possible favorable role of beta-blockers in improving the prognosis of patients. The mechanisms behind a possible beneficial effect are speculative and may include inhibition of angiogenesis, stimulation of T-cell recruitment, increases in the production of proinflammatory cytokines, and induction of immune activation. However, meta-analyses have yielded conflicting results. Read more.

Effect of Acupuncture on Aromatase Inhibitor-Induced Arthralgia in Breast Cancer
Aromatase inhibitors are standard treatments for reducing breast cancer recurrence in postmenopausal women and hormone receptor–positive patients. However, their use is associated with treatment-limiting arthralgias. Nonpharmacologic modalities that can relieve this pain without exposing patients to the side effects of drug therapy would be ideal. Read more.

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