August 2020

Chemotherapy and Survival in Patients Aged 70 Years or Older 

Aging is associated with an increase in the incidence of breast cancer (BC) and the prevalence of comorbidities, which can complicate decisions about initiating chemotherapy. Further, older adults with multiple comorbidities are often excluded from clinical trials, adding difficulty to therapeutic decision making. As a result, there has been insufficient data to make definitive chemotherapy recommendations for the management of BC in women aged 70 years or older. Read more.


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Breast Cancer Survivorship and Increased CVD Risk
Among breast cancer (BC) survivors aged 50 years and older, cardiovascular disease (CVD) accounts for 35% of noncancer-related deaths and is a leading cause of death. Drug toxicity from previously administered chemotherapeutic agents (such as anthracyclines or from biological agents), lifestyle factors (such as physical inactivity, obesity, and alcohol use), and hormonal factors (for example, insulin resistance or endocrine therapy) contribute to the development of CVD. Read more

Understanding Male Breast Cancer
Breast cancer in males accounts for about 1% of all breast cancer cases. Due to its rarity, not much is known about this disease. To help add to the knowledge about this condition, two recent studies, one from the United States and the other from Brazil, were conducted that examined features of the disease, including treatment patterns, prognostic factors, age and stage at time of diagnosis, and histology. Read more

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