Global Assessment Reveals HoFH Frequently Undertreated
In a recent study, researchers attempted to evaluate the clinical and genetic characteristics, as well as the global impact, of current practice on health outcomes of the rare, inherited disorder known as homozygous familial hypercholesteremia (HoFH). Researchers indicated that HoFH is often undertreated—especially in lower income countries—and is sometimes diagnosed after atherosclerosis or aortic stenosis is already present. Read more.
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FDA Approves Twice-Yearly Injectable Drug to Lower LDL-C Levels
The manufacturer, Novartis, announced that the FDA approved Leqvio (inclisiran), the first and only small interfering RNA (siRNA) therapy to lower low-density lipoprotein cholesterol (LDL-C) with two doses a year after an initial dose and 1 at 3 months in patients with atherosclerotic cardiovascular disease or heterozygous familial hypercholesterolemia. Learn more about this first-of-its-kind siRNA therapy.
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