April 2020

Demystifying Acetaminophen Side Effects Amid COVID-19
The coronavirus outbreak increases the demand for symptom management, including fever reduction. Acetaminophen (APAP) is widely accepted as a go-to antipyretic; however, a relatively common side effect of serious hypotension associated with parenterally administered APAP limits its use and has sparked some hesitancy, especially among those treating critically ill patients. In a study, scientists attempt to learn how avoid this adverse effect. Read more.


Antidepressant Repurposed for Recurrent Prostate Cancer
The chance that an old antidepressant could represent a novel treatment in the fight against prostate cancer is becoming reality. In an article in Prostate Cancer and Prostatic Diseases, researchers explore the impact of monoamine oxidase (MAO) on cancer growth and to what degree inhibiting MAO can influence outcomes, including metastasis in patients with certain forms of prostate cancer. Read more.

Analgesic Efficacy Compromised in Gut Microbiome
Can changes to the gut microbiome alter the effectiveness of pain relievers? New research is suggesting this is possible, and even likely. In research published in Nature Scientific Reports, study authors examined how changes in the bacterial composition in the gastrointestinal system can not only influence side effects of drugs ingested, but also may compromise how well they work for the purposes prescribed. Read more.

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