Norepinephrine Superior to Epinephrine for PRS Following OHCA Epinephrine and norepinephrine are the drugs of choice for continuous intravenous vasopressor therapy to manage post-resuscitation shock (PRS). However, in patients who sustain PRS after out-of-the hospital cardiac arrest (OHCA), it is unclear if one agent is preferred over the other. This is important, as survival after OHCA is only about 10%. Read more.
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IVT in AIS in Patients With Prior ICrH
While the American Heart/Stroke Association still categorizes a history of intracranial hemorrhage (ICrH) as a contraindication to the use of intravenous thrombolysis (IVT), this alert was removed from alteplase's prescribing information due to lack of evidence. This renders the use of IVTs in acute ischemic stroke (AIS) patients with prior intracranial hemorrhage somewhat controversial. Read more.
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