May 2022

Smart Pump Interoperability and Impact on Medication Errors
The use of smart pump technology has improved quality and safety during the administration of IV medications; however, problems with medication errors still exist. In an attempt to further reduce their occurrence, smart pump technology has been integrated with the electronic health record. However, information is limited on whether smart pump interoperability has decreased harm. Read more.


Intramuscular Versus Intra-articular Corticosteroid Injections for Knee Osteoarthritis
The use of intra-articular corticosteroids is often recommended when patients with osteoarthritis of the knee fail oral or topical analgesic therapy. The safety of intra-articular steroid injections has been called into question as these agents can be associated with greater cartilage loss and an increased risk for septic arthritis. Clinicians have attempted to use IM corticosteroids as an alternative route of administration. Read more.

Neurologic Adverse Events Associated With Immune Checkpoint Inhibitors
Immune checkpoint inhibitors (ICIs) block the inhibitory pathways of T-cell activation, which allows T cells to recognize tumor antigens to generate an antitumor immune response. While this class of immunomodulatory agents have revolutionized the treatment of oncologic diseases, there is concern about its potential for neurologic adverse events (NAEs), which can be fatal. Learn more about the risk of NAEs associated with ICIs.

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