U.S. Pharmacist Weekly News Update
July 18, 2018

Algorithm Can Determine Who Benefits From Aggressive Hypertension Treatment

Aggressive hypertension treatment isn’t for everyone, but how can it be determined who will benefit most? A new algorithm provides the answer, using three variables routinely collected during clinical visits as predictors. Here is more information.


Metformin Appears Safe for Some T2D Patients With Chronic Kidney Disease
Patients who have comorbid type 2 diabetes and chronic kidney disease often aren’t prescribed metformin because of fears about lactic acidosis. A new study suggests that in at least some of those patients, the concerns might be unfounded and metformin might be safe to use. Here is what the study team determined. 

Study Dashes Hopes for Antioxidant Treatment for Male Fertility Issues
Pharmacists questioned about use of antioxidants to improve male fertility have some bad news to share: A combination of vitamins and other supplements didn’t improve sperm concentration, motility, or morphology in a recent study. Here is what else the conference presentation reported.

Meta-Analysis Questions Widespread Use of Gabapentinoids for Back Pain
Despite guideline recommendations against their use, drugs such as gabapentin and pregabalin continue to be prescribed at high rates for back and neck pain. An Australian meta-analysis suggests that moderate-to-high evidence exists for their ineffectiveness. Here is more information.


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