U.S. Pharmacist Weekly News Update
November 13, 2019

Taking Antihypertensives
at Bedtime Improves BP
Control, Survival

Pharmacists now have some valuable information to offer to patients being treated for high blood pressure (BP): time of treatment matters, according to a new study. Find out the best time to take antihypertensives and why it is important.


No Higher Rates of Exacerbation in COPD Patients Who Are Using Beta-Blockers
The use of beta-blockers in patients with COPD had been fraught with controversy, although observational studies suggest that is safe and might even reduce the risk of exacerbations and death. Now, a new prospective, randomized trial finds little difference in increased risk of exacerbations in those taking metoprolol, but couldn’t identify any benefits, such as decreased risk of death. Here is more information.

A Third of DOAC Users Also Ingest OTC Products With Potential Interactions
Patients taking direct-acting oral anticoagulants (DOACs) don’t have to go to clinics for regular testing, as with warfarin. An unintended consequence is that knowledge about potential drug reactions with OTC products is limited. A new study provides information that pharmacists could use to help patients. Here are more details.

Kidney Injury Often Occurs With Immune Checkpoint Inhibitor Cancer Therapy
The use of immune checkpoint inhibitors for cancer is increasing. While the cutting-edge therapy can have significant benefits, it has risks, chief among them acute kidney injury, according to a new study. Find out how often that occurs and what exacerbates the problem.

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