April 10, 2024

Paxlovid Efficacy Not Established for Certain Cohorts

Pharmacists often encounter patients who have tested positive but are not at an elevated risk for severe COVID-19 and now want a prescription for Paxlovid. Find out why a new study suggests that might not be a good idea, explaining that the efficacy of the nirmatrelvir-ritonavir combination has not been established in that cohort.

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RSV Severity Comparable to COVID-19, Flu in Unvaccinated Adults

The lack of a clear public health directive for older adults to receive a respiratory syncytial virus (RSV) vaccine might suggest otherwise, but a new study found that before the approval of the vaccines, cases of RSV were at least as severe as COVID-19 or influenza among unvaccinated patients and were actually more severe than in those who were  hospitalized after having been vaccinated against flu and COVID-19. Read more.

New Injectable Antibiotic Approved to Treat Three Difficult Infections

Staphylococcus aureus bloodstream infections in adults, acute bacterial skin and skin structure infections, and community-acquired bacterial pneumonia in adults and pediatric patients (aged 3 months and older) can be notoriously hard to treat, especially in a hospital setting. Now, the FDA has approved a new injectable antibiotic, ceftobiprole medocaril sodium, to battle those infections. Read more.

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Use of IV Vasoactive Drugs, Albumin in Cirrhosis

In patients with decompensated cirrhosis and/or variceal hemorrhage, vasoconstrictors decrease portal pressure by causing splanchnic vasoconstriction. To address developments in the management of cirrhosis, the American Gastroenterological Association released a clinical practice update with best practice recommendations for the use of IV vasoactive drugs and IV albumin in three areas. Read more.

 
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