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Disparities in DOAC Prescriptions Diminished Over Time
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For nearly a decade after the approval of direct oral anticoagulants (DOACs), black and Hispanic patients were less likely to have been prescribed them. Those inequities have now mostly dissipated, however. The authors suggest that a study published in the Journal of the American Medical Association Network Open can help avoid future racial/ethnic discrimination in the use of medications. Read more.
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Higher Dementia Risk From TCAs in Older Patients
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Older patients who are prescribed tricyclic antidepressants (TCAs) at Federal Qualified Health Centers are at risk of receiving dosages that exceed risk thresholds for dementia. Find out how the authors determined that patients, who usually received the drugs for diabetic peripheral neuropathy, might have received a strength, frequency, or duration that made the patient more likely to suffer cognitive decline.
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SGLT2i Benefits T2D Patients With Kidney Disease
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In a recent study, patients with the common combination of type 2 diabetes (T2D) and chronic kidney disease benefited from using sodium-glucose cotransporter-2 inhibitors (SGLT2i). The results indicate that SGLT2i use was associated with lower risks for dialysis, hospitalization for heart failure, acute myocardial infarction, and acute kidney injury compared with no SGLT2i use. Read more.
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Influenza Vaccine Safety Profile in Older Adults
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In response to concerns about adverse events from flu shots in the 2022–2023 season, public health officials examined the safety of the vaccines in U.S. adults aged 65 years and older. While there was a slight increase in anaphylaxis cases, the researchers determined that rates of encephalitis/encephalomyelitis, Guillain-Barré Syndrome, or transverse myelitis were not elevated following 2022–2023 seasonal influenza vaccinations. Read more.
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