June 23, 2021

Some Statins Appear to Increase Dementia in Patients With Mild Cognitive Issues

Some of the most commonly prescribed statins are in the lipophilic category. That’s why a new study is raising concerns. Find out how researchers determined that patients with early mild cognitive impairment and low-to-moderate serum cholesterol levels at baseline had more than twice the risk of developing dementia over 8 years of follow-up with lipophilic statins vs. no statin use.

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Prophylactic Anticoagulation Strategies Appear Optimal for COVID-19 Inpatients

Early on in the COVID-19 pandemic, evidence began to mount that the use of anticoagulants improved outcomes. What was unclear was whether prophylactic- and treatment-dose anticoagulation were better for associated venous thromboembolism (VTE). Here are more details from a study that helps answer that question while looking at how hospitals managed VTE prevention in novel coronavirus patients.

No Outcomes Differences With Adalimumab Biosimilar in IBD Patients

Since 2017, the FDA has approved about 30 biosimilars, but unanswered questions remain about their use. A recent study looked at how inflammatory bowel disease patients fared when they were switched from brand-name adalimumab to a biosimilar. Here is what they determined.

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Researchers Suggest COVID-19 Circulated in United States by December 2019

The SARS-CoV-2 virus appears to have been circulating in the United States well before pharmacists and other healthcare professionals were aware of it. An NIH-sponsored study finds evidence that it was in states far from the assumed ports of entry—Seattle and New York—in December 2019, with pandemic shutdowns still months away. Here is more information.

 
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