US Pharm. 2006;11:20-28.
Agitation (increased verbal and/or
motor activity as well as restlessness, anxiety, tension, and fear) and
aggression (self-assertive verbal or physical behavior arising from innate
drives and/or a response to frustration that may manifest by cursing/threats
and/or destructive and attacking behavior toward objects or people) are
symptoms commonly present in patients with central nervous system (CNS)
disorders.
For example, patients with dementia present
with cognitive impairment as well as behavioral and psychological symptoms,
including agitation, aggression, irritability, delusions, sleep disorders,
anxiety, and phobias.1 The most common form of dementia,
Alzheimer