Published October 20, 2010 ONCOLOGY Low-Dose Aspirin Protects Against Bowel Cancer By Staff US Pharm. 2010;35(10):HS-32. Taken regularly, even the lowest possible dose of aspirin (75 mg) can fight off bowel cancer, finds research published online in the journal Gut. This effect is apparent after just 1 year and in the general population, not just in those considered to be at risk for developing the disease. Bowel cancer is the second most common cause of cancer death in the world, killing almost half a million people annually.