US Pharm. 2013;38(1):7.

Madison, WI—A longitudinal study by the University of Wisconsin School of Medicine and Public Health found a small but significant increase in the risk of neovascular age-related macular degeneration (AMD) with regular aspirin use 10 years prior. Nearly 5,000 subjects aged 43 to 86 years at entry received retinal examinations every 5 years over a 20-year period and were asked whether they had regularly used aspirin at least twice weekly for more than 3 months. Over the study period, 512 incident cases of early AMD and 117 incident cases of late AMD (neovascular and pure geographic atrophy [GA]) occurred. Neovascular AMD was associated with regular aspirin use 10 years prior (1.4% of regular aspirin users), but pure GA and early AMD were not.

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