U.S. Pharmacist Weekly News
April 3, 2024

Major Bleeding With Concomitant SSRI, OAC Prescriptions

Concomitant prescriptions for selective serotonin reuptake inhibitors and oral anticoagulants should raise some concerns for pharmacists, based on the findings of a new study published in the Journal of the American Medical Association. The researchers identified an increased risk of major bleeding among atrial fibrillation patients with dual use of the drugs compared with oral anticoagulant use alone. Read more.


Valproate Use During Pregnancy Linked to Autism in Children

While evidence might have been less certain in the past, a new study makes it clear that the antiseizure drug valproate presents significant risks when used by pregnant women. Find out the strength of the link between use of valproate and the development of autism spectrum disorder in offspring—as well as other issues—compared with alternative medications.

Inappropriate Diagnosing of Community-Acquired Pneumonia

A relatively high rate of inappropriate diagnosis of community acquired pneumonia in hospitalized patients is putting some older adults at risk, according to a new study. The common use of a full course of antibiotics can lead to adverse effects, according to the authors, who list a range of other potential issues. Read more.


Migraines Play Role in Strokes Suffered by Younger Adults

The risk factors for stroke appear to be quite different for younger versus older adults, according to a new report. Find out how researchers determined that those aged younger than 45 years—especially women—might have a higher risk of developing a stroke from nontraditional risk factors than from traditional issues, such as high blood pressure.

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